Anti-inflammatory Effect of Scopoletin in RAW264.7 Macrophages
نویسندگان
چکیده
منابع مشابه
Anti-inflammatory effect of pristimerin on TNFα-induced inflammatory responses in murine macrophages
Purpose: To investigate the anti-inflammatory effect of pristimerin using RAW 264.7 macrophage cells. Methods: The effect of pristimerin on the RAW 264.7 cells proliferation was determined by CCK8 test. The expression of cyclin D1 and cyclin E1 in RAW 264.7 cells treated with TNF-α and pristimerin was measured by qRT-PCR. The regulation of cytokine IL-1β, IL-6, IL-8, and PGE2 in RAW 264.7 cells...
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Crotalaria juncea (Leguminoceae) has been used for its antiarthritic effect in the folklore medicine. The purpose of this study was investigating experimentally the possible antiarthritic and antiulcerogenic properties of Crotalaria juncea leaves in animal model. Ethanolic extract of Crotalaria juncea (CJE) was administered at the doses of 200 and 400 mg/kg to complete Freund’s adjuvant (...
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Bioassay guided fractionation of an ethanol extract of leaves of Canarium patentinervium Miq. (Burseraceae Kunth.) led to the isolation of scopoletin. The structure of this coumarin was elucidated based on spectroscopic methods including nuclear magnetic resonance (NMR-1D and 2D) and mass spectrometry. Scopoletin inhibited the enzymatic activity of 5-lipoxygenase and acetyl cholinesterase with ...
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Objective(s) Using herbal medicines as a complementary treatment method is increasing in wide variety of diseases. MS14-an herbal-marine preparation-is reported to have anti-inflammatory and immunomodulatory activities; however, the mechanism underlying its therapeutic effect is not known. Macrophages play an important role in host defense mechanisms and carry out their role by producing vario...
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ژورنال
عنوان ژورنال: Journal of Life Science
سال: 2015
ISSN: 1225-9918
DOI: 10.5352/jls.2015.25.12.1377